The Ministry of Health of Russia has allowed the NF Gamaleya Center to begin clinical trials of the “light version” of the Sputnik V vaccine. It is called Sputnik Light and is also designed to fight the coronavirus. As noted in the message of the department, trials begin to assess the safety, tolerability and immunogenicity of the drug. What is known about the drug “Sputnik Light”, which is planned to be used as a prophylaxis for coronavirus infection caused by the SARS-CoV-2 virus.
For the first time, the light version of the main vaccination, which was created by the Gamaleya Institute, was announced at a press conference Vladimir Putin, who noted that Russia is considering the possibility of such an option with an efficiency of up to 85%. The head of state noted that tens of millions of people could be inoculated with such a lightweight version at once. True, the light vaccine will have a shorter protection period than Sputnik V.
Alexander Gintsburg, Head of the Gamaleya Center, noted that the vaccine preparation “Sputnik Light” “allows you to offer a compromise between the duration of action of the vaccine preparation” Sputnik V “, which apparently has a very good duration of action, and the need to quickly bring down the peak of incidence.” At the same time, he stressed that it is not even about morbidity, but mortality from a new type of coronavirus. Alexander Gintsburg spoke about the new development in an interview with the Russia 24 channel.
Sputnik Light uses only one component of the main drug – one strain of adenovirus. One of the Chinese developments was made on a similar principle. Accordingly, such a vaccine will be administered in the form of a single shot. It is worth recalling here that the main “Sputnik V” requires a double injection with a break of a couple of weeks, since it is a two-component.
Using the lite version will help you reach a larger population and prevent deaths. “The duration of the action will be short. But this is a certain compromise due to the fact that no industry in any country can simultaneously produce all the required amount of vaccines, ”Gintsburg emphasized.
The scientist noted that from a single-component vaccine, immunity will be formed for up to 3-4 months. “If a person gets sick after a light vaccine, he will not have a severe form of the disease. The causative agent of the virus will not descend into the lungs, everything will end at the level of acute respiratory infections, ”RIA Novosti quotes Alexander Gintsburg.
After three months, those who wish can supply the second component of the vaccine, thereby strengthening their protection and further strengthening the immune system after a new type of infection. At the same time, the priority vaccination option, as noted by Alexander Gintsburg, still remains the use of “Sputnik V” as a drug that gives stronger and longer-lasting immunity, as well as contributes to the appearance of memory cells.
“Clinical trials of the light vaccine in certain age groups will naturally be required,” noted Alexander Gintsburg. “Its safety has been fully proven, and its effectiveness in different age groups, of course, requires additional study.” For example, the scientist noted that people over 40-50 years old are already better off using the two-component, and not the light version.
Sputnik Light tests will start on the basis of three sites and will last until the end of 2021.
There are contraindications, it is necessary to consult a doctor