Dec 30, 2020
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What is the difference between Sputnik V and EpiVacCorona vaccines?

Two vaccines against coronavirus have appeared in Russia today – “Sputnik V”, created at the Gamaleya Institute, and “EpiVacCorona”, developed by the Novosibirsk center “Vector”. As noted, both are already supplied to the regions. This raises the question: how do they differ?

““ Sputnik ”may be a little more reactogenic than the“ vector ”, Novosibirsk vaccine, but neither one nor the other has any serious side effects. They are completely different – one vector based on adenovirus, the other peptide, made from three constituent parts of the coronavirus genome, which are most resistant to mutation. It develops a humoral response, ”said Deputy Prime Minister Tatiana Golikova

“Sputnik V”

The Sputnik V trademark hides the Gam-COVID-Vac vaccine. This is a two-component development from a new type of coronavirus infection, which was created jointly by the FSBI NITsEM named after NF Gamalei “of the Ministry of Health of the Russian Federation and the Federal State Budgetary Institution” 48th Central Research Institute “of the Ministry of Defense of Russia. The vaccine is a recombinant adenovirus particle as well as a coronavirus spike protein. It is this combination that should stimulate the production of antibodies. It uses the 26th serotype of adenovirus as a basis. This vaccine is injected twice intramuscularly, the interval is several weeks.

As previously noted in the Ministry of Health, a two-time vaccine administration scheme will allow the formation of long-term immunity. According to the experience of application, experts say, the protective forces last for about 2 years. In this case, we are talking specifically about the two-time use of the vector vaccine.


This is a single-component peptide vaccine developed by the State Scientific Center for Virology and Biotechnology Vector of Rospotrebnadzor. It is a chemically synthesized development in the form of peptide antigens of three different proteins of the virus called Sars-CoV-2. They are conjugated to a carrier protein. This vaccine contains no preservatives or antibiotics. The vaccine is administered twice intramuscularly, the interval between stages is 14-21 days.

The vaccine developers assume that immunity will last for at least six months. Accordingly, revaccination will be required in 6-10 months. And in the future, as noted by representatives of the developer, it will be possible to undergo repeated vaccinations every three years.

There are contraindications, it is necessary to consult a doctor.

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