According to Pharmvestnik, the ethics committee made this decision to cancel the study of the joint use of the AstraZeneca and Sputnik V vaccines on May 11. Interfax reports that the corresponding document has been published on the website of the Ministry of Health.
Pharmvestnik contacted representatives of AstraZeneca, who told the publication that they had not received an official response from the committee, but “are ready to cooperate, since we are firmly convinced of the benefits of the heterogeneous boosting strategy and its enormous importance in combating the pandemic̆”.
Preparation of a study on joint use of British and Russian vaccines against COVID-19 for the first time reported in December 2020. This was to be a phase I-II study that would show the combination is safe and able to stimulate the production of immunity against the coronavirus. According to “Pharmvestnik”, it should have been held in Belarus and Russia. It was assumed that the study will have two groups of volunteers. One had to first receive an injection of the vaccine manufactured by AstraZeneca, and on the 29th day after the first injection, the first component of Sputnik V. In the second, the sequence of drug administration was different.
In April 2021, the European Medicines Agency announced that there was a link between the use of the AstraZeneca COVID-19 vaccine and the incidence of thrombosis.
To date, there have been no comments from the Ministry of Health regarding the cancellation of the study.