Apr 19, 2021
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The effectiveness of Sputnik V according to the results of vaccination was estimated by 3.8 million Russians at 97.6%

According to the RDIF, information on the incidence was obtained from the Unified State Information System in Healthcare (Unified State Health Information System) of the Ministry of Health of Russia, which maintains a register of citizens who have received the vaccine, as well as patients with COVID-19.

The analysis includes data on 3.8 million Russians who received both doses of the vaccine from December 5, 2020 to March 31, 2021. The results showed that the incidence among those vaccinated from day 35 after the first injection was only 0.027%. The developers did not report any adverse reactions or deaths after vaccination.

At the same time, the incidence rate in the unvaccinated adult population in the same period (35 days after the start of mass vaccination) was 1.1%. Based on these data, the developers have estimated the effectiveness of Sputnik V at 97.6%. An interim analysis of Phase III clinical trials of the vaccine, published in The Lancet in February, showed an efficacy of 91.6%.

Director of the Center. Gamalei Alexander Gintsburg noted that this indicator may be even higher, since the data of the registration system for cases allow a time lag between the sampling (the actual date of the disease) and the diagnosis.

At the moment, scientists are preparing an article with detailed data and calculations in a peer-reviewed medical journal, publication is planned for May, the RDIF reported.

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