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Dec 30, 2020
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Obesity linked to increased risk of SARS-Cov-2 infection – study

Obesity and Risks to the Respiratory System

It is known that patients with a high body mass index often have respiratory dysfunction, which is characterized by changes in respiratory mechanisms, increased airway resistance, impaired gas exchange, and low lung volume and muscle strength. Obesity is also associated with an increased risk of diabetes, cardiovascular and kidney disease, and other diseases that lead to an increased vulnerability to pneumonia.

The conclusions of scientists are confirmed by doctors: head. the department of anesthesiology and resuscitation of the N.M. Pirogov Boris Teplykh talked about the fact that obese patients require longer periods of treatment in an intensive care bed in covid hospitals.

New research

In a new study, scientists from the University of Miami assessed the effect of obesity on the production of IgG antibodies against SARS-CoV-2. The study authors measured antibody levels in patients with COVID-19 and people in a control group, which included uninfected participants.

The authors of the study found that in those infected, the level of antibodies against coronavirus was negatively associated with body mass index (BMI). That is, in people with obesity, their level was lower than in those whose weight was normal.

At the same time, the fewer antibodies against coronavirus were in patients with COVID-19, the higher the level of inflammatory markers in their blood was, in particular – markers of inflammation in the lungs. Thus, obese patients are at increased risk of a severe complication of coronavirus infection – acute respiratory distress syndrome.

According to the researchers, these findings should be used to develop effective treatments for these patients. In addition, overweight patients should have a priority right to vaccination, scientists say.


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