Jun 22, 2022
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Gut health affects heart failure

Gut health affects heart failure

In a new study led by Georgetown University Medical Center, scientists have established a link between gut health and cardiovascular health. The study looked at heart failure, an end-stage heart disease that affects more than six million people each year. Cardiovascular disease is the leading cause of death in the US.

For the study, the researchers analyzed the results of 511 past studies. They focused on a harmful metabolite known as trimethylamino-N-oxide (TMAO). This metabolite is formed in the presence of red meat, full-fat dairy products, and egg yolks.

Experts have found that people suffering from heart failure have an increased presence of intestinal metabolites, which is associated with an increase in hospitalizations and an increase in mortality. Bacteria, viruses, fungi, and protozoa make up the complex and delicate gut microbiome. The researchers also found that patients with heart failure often have a less biodiverse gut.

However, due to a lack of data, scientists were unable to determine the interaction between the microbiome and the cardiovascular system. They noted that proper nutrition is associated with a healthy cardiovascular system and that researchers should continue to study this issue.

The experts hope this study will encourage other researchers to learn more about how the gut and vascular system affect each other.

“For the diagnosis and treatment of heart failure, we rely on certain data and test results, but we do not know how poor heart function affects bowel activity, including the absorption of food and drugs,” said study co-author Kelly Anderson.

“There is now an understanding of the relationship between the heart and the elements of the gut, as it is clear that the cardiovascular system does not work in isolation – the health of one system can directly affect the other, but clear links are still being worked out scientifically.”

“We are currently developing a prospective study to assess the microbiome in patients with heart failure. We are particularly interested in the symptomatology of patients with end-stage heart failure, as well as disease-related weight loss and wasting in this stage of cardiovascular disease.”

The study is published in Heart Failure Reviews.

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Comments to Gut health affects heart failure

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    24LUkLncTnulK June 23, 2022 7:58 pm Reply

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