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Oct 14, 2021
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Deficiency of an essential thyroid hormone can trigger suicidal thoughts

Nothing pleases, the whole world is in black and you even want to die? Perhaps you should not only see a therapist, but also check thyroid-stimulating hormone (TSH) levels, according to the authors of a new study.

Thyroid stimulating hormone (TSH) is the main regulator of thyroid function, synthesized by the pituitary gland. It also stimulates the synthesis of triiodothyronine (T3) and thyroxine (T4), which provide energy balance in the body, affect the motor function of the intestines, the menstrual cycle, the state of hearing and vision, and are responsible for the functioning of the central nervous and cardiovascular systems. When TSH levels are low, a person may experience irritability, insomnia, anxiety, leg swelling, and other serious symptoms.

Scientists from the Lithuanian University of Medical Sciences presented their scientific work at the congress of the European College of Neuropsychopharmacology (ECNP), Medscape reports. Experts recalled that thyroid hormones have a significant effect on emotions and mood, and recent studies have identified a link between their deficiency and suicidal behavior in patients with depression.

To confirm this link, the researchers examined the thyroid hormone profile in 77 patients aged 18-73 who attended a stress disorder clinic. All volunteers underwent a series of tests to determine symptoms of depression and anxiety. The presence of suicidal thoughts and moods was reported by 42 people.

All participants had blood samples taken and their TSH, (T4) and (T3) levels checked. The results showed that patients with suicidal ideation had, on average, decreased TSH levels. At the same time, scientists did not find a connection between suicidal thoughts and the level of other thyroid hormones.

After adjusting the data for gender, age, body mass index, and lifestyle factors, the researchers concluded that suicidal people had a 54% chance of being TSH deficient.

“These results may be important in preventing suicide and allow clinicians to assess the likelihood of developing suicidal thoughts in people with anxiety and emotional disorders,” the study authors said.


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