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Nov 23, 2021
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Aspirin Linked to Increased Risk of Cardiovascular Failure

Aspirin, or rather acetylsalicylic acid, is one of the oldest drugs in the world. It was used by the ancient Egyptians, who boiled willow bark to obtain it. But only from the beginning of the nineteenth century, the substance began to receive purposefully. In 1899, Bayer chemist Felix Hoffmann isolated and purified a drug that became a hit with patients. Today, aspirin is one of the most popular drugs in the world, second only to adhesive plaster and citramone in popularity. Pharmaceutical companies sell up to 80 billion tablets a year.

Scientists have been talking about the dubious effectiveness of aspirin for some time. Earlier research suggests the drug can cause severe internal bleeding. At the same time, the drug is prescribed for the prevention of heart attacks and strokes, however, it turned out that although taking it reduces the risk of heart disease in healthy people by 17%, but at the same time, the likelihood of gastrointestinal bleeding in them increases by 47%, and intracranial hemorrhage – by 34%. In addition, the risk of bleeding in the stomach doubles if it is infected with Helicobacteria (70% of Russians have them).

The current study has shown that aspirin can even be harmful and cause cardiovascular failure. The risk reaches 26% in people with obesity, smokers, high blood pressure and cholesterol levels, diabetes, or a history of various heart and vascular diseases. Scientists believe that aspirin should be used with caution in these patients, as well as those who already suffer from cardiovascular failure.

The study used data from more than 30 thousand people at risk of developing cardiovascular failure. Participants were over 40 years of age and did not suffer from CHF when included in the sample. Scientists also took into account whether patients were taking aspirin. The average age of the participants was 67, of whom 34% were women. 7,698 participants (25%) took aspirin at baseline. Over 5.3 years of follow-up, 1,330 participants developed heart failure.

Also, earlier studies have established a possible link between aspirin and cancer. For children, the drug is not recommended by doctors in the United States and Great Britain. In young patients, Reye’s syndrome can develop – fatal in 31% of cases.

The ability of aspirin to thin blood and prevent blood clots was discovered by American physician Lawrence Craven. He noticed that his patients, who chewed acetylsalicylic acid gum, suffered from internal bleeding. The doctor decided that it was this property of the drug that could help prevent heart attacks and strokes. He published an article on this in 1956, but it went unnoticed. And to aspirin as a drug for the heart returned only at the end of the twentieth century.


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